İSIM |
TEZ TÜRÜ |
MEZUNIYET YILI |
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RIFAT ÜNGÖR |
Yüksek lisans |
2017 |
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ILAHA MUSAYEVA |
Yüksel lisans |
2017 |
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NİCAT CEBRAİLOĞLU |
Yüksek lisans |
2017 |
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KADER ÇİÇEK |
Yüksek lisans |
2018 |
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TAHA TANGUT |
Yüksek lisans |
2018 |
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BURCU GÜLEÇ |
Yüksek lisans |
2018 |
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RABİA AKÇORA |
Yüksek lisans |
2019 |
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SONER AKBURU |
Yüksek lisans |
2020 |
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ESMIRA MIRZALIYEVA
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Yüksek lisans |
2020 |
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DENİZ SAY |
Yüksek lisans |
2020 |
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DAMLA YÜKSEL |
Yüksek lisans |
2020 |
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İREM GÜRBÜZASLAN |
Yüksek lisans |
2021 |
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NİLÜFER GÜN |
Doktora |
2021 |
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RAMAZAN TALHA PALAZ |
Yüksek Lisans |
2022 |
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BERFİN ÜLGEN |
Yüksek Lisans |
2022 |
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MERVE ILGIN |
DOKTORA |
2023 |
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FADİME DEMİREL |
DOKTORA |
2023 |
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ÖZLEM BABACAN |
YÜKSEK LİSANS |
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EYLÜL BİLGE SARI |
YÜKSEK LİSANS |
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DAMLA YÜKSEL |
DOKTORA |
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BURCU GÜLEÇ |
DOKTORA |
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ŞEREF ERDEM |
YÜKSEK LİSANS |
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AYSU-SHOVKAT HASANOVA |
Visiting internship From Institute of Molecular Biology and Biotechnologies, Azerbaijan National Academy of Sciences |
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PROJELER
1. Yeşil Mikro Alg Chlamydomonas Reinhardtii de CO2 Fiksasyon Metabolizmasının Denetiminin Biyokütle ve Biyoyakıt Üretimini Arttırmak için Değiştirilmesi. TUBITAK 1001, 214Z118 , 01/10/2015 - 01/10/2017.
2. Nicotiana Benthamiana Bitkisinde Aktif İnsan Faktör Ix Rekombinant Proteini Üretimi. TUBITAK 1001, 114Z863 , 15/04/2015 - 15/04/2018.
3. Pfs48/45 Aşı Adaylarının Deglikosile Biçimlerinin Dizaynı, Üretimi ve Karakterizasyonu . TUBITAK 1001, 114Z258, 15/10/2014-15/10/2017.
4. Şarbona Karşı Aşı Adayı Olarak Kullanılabilir Koruyucu Antijen (PA)’nın Bitkide Üretilmiş Deglikosile Formunun Üretimi, Karakterizasyonu ve Klinik Öncesi Değerlendirilmesi. TUBITAK 1003, 115S077, 01/12/2015-01/08/2021,
5. Kuduza Karşı Bir Aşı Adayı Olarak Bitkilerde Üretilmiş G Proteini Varyantlarının Mühendisligi, Üretimi ve Karakterizasyonu. TUBITAK 1001, 218S723, 01/04/2019-01/04/2022.
6. Oldukça patojenik SARS-CoV-2 koronavirüsüne karşı aşı adayı olarak spike proteinlerinin farklı varyantlarının mühendisliği, üretimi, karakterizasyonu ve klinik öncesi değerlendirilmesi. TUSEB-8611, 01/12/2020-01/12/2021.
7. PFS25 Ve PFS230 Aşı Adaylarının Deglikosile Edilmiş Formlarının Mühendisliği, Üretimi Ve Karakterizasyonu. TUBITAK 1001, 222Z043, 01/04/2023-devam ediyor.
MAKALELER
1. Mamedov T, Yuksel D, Gurbuzaslan I, Ilgin M, Gulec B, Mammadova G, Ozdarendeli
A, Pavel STI, Yetiskin H, Kaplan B, Uygut MA and Hasanova G (2023). Plant-produced
RBD and cocktail-based vaccine candidates are highly effective against SARS-CoV-2,
independently of its emerging variants. Front. Plant Sci., Volume 14. doi:
10.3389/fpls.2023.1202570
2. Mammadova, G., Gurbuzaslan, I., Yuksel, D., Gun, N., Mutlu, N., Hasanova, G., and
Mamedov, T. Engineering, production, and immunogenicity studies of a truncated form
of rabiesvirus glycoprotein produced in Nicotiana benthamiana plant . Med Science
2022;11(2):478-83.
3. Gun, N., & Mamedov, T. (2021). Flexible approaches are required for successful
production of recombinant proteins in plants . Medicine Science 11 (1), 447-51.
4. Mamedov et al. Plant-produced RBD and cocktail-based vaccine candidates are highly
effective against SARS-CoV-2, independently of its emerging variants , BioRxiv, 2022.
5. Mamedov T, Gurbuzaslan I, Yuksel D, Ilgin M, Mammadova G, Ozkul A and Hasanova
G. Soluble Human Angiotensin-Converting Enzyme 2 as a Potential Therapeutic Tool for
COVID-19 Is Produced at High Levels In Nicotiana Benthamiana Plant With Potent
Anti-SARS-CoV-2 Activity . Frontiers in Plant Science, 2021, DOI:
10.3389/fpls.2021.742875
6. Mamedov, T.; Yuksel, D.; Ilgın, M.; Gürbüzaslan, I.; Gulec, B.; Mammadova, G.;
Ozdarendeli, A.; Yetiskin, H.; Kaplan, B.; Islam Pavel, S.T.; et al.Production and
Characterization of Nucleocapsid and RBD Cocktail Antigens ofSARS-CoV-2 in
Nicotiana benthamiana Plant as a Vaccine Candidate against COVID-19 in Vaccines,
2021, https://doi.org/10.3390/vaccines9111337 .
7. Mamedov, T.; Yuksel, D.; Ilgın, M.; Gurbuzaslan, I.; Gulec, B.; Yetiskin, H.; Uygut,
M.A.; Islam Pavel, S.T.; Ozdarendeli, A.; Mammadova, G.; et al. Plant-produced
glycosylated and In vivo Deglycosylated receptor binding domainproteins of SARS-
CoV-2 induce potent neutralizing responses in mice . In Viruses,
2021,https://doi.org/10.3390/v13081595
8. Mammedov, T.,Gurbuzaslan, I., Ilgin, M., Yuksel, D., Mammadova, G., Ozkul, A.,
Hasanova, G. High level production and characterization of truncated human angiotensin
converting enzyme 2 in Nicotiana benthamiana plant as a potential therapeutic target in
COVID-19. bioRxiv 2021.05.17.444533; doi: 10.1101/2021.05.17.444533
9. T Mamedov, B Gulec, G Mammadova. Plant molecular pharming is a promising system
for cost-effective production of veterinary vaccines . Mediterranean Agricultural Sciences
33 (3), 375-380.
10. T Mamedov, I Soylu, G Mammadova, H Gulnara. Sequence analysis and amino acid
variations of structural proteins deduced from Novel Coronavirus SARS-CoV-2 strains,
isolated in different countries . Preprint 1.2020.
11. T Mammedov, D Yuksel, M Ilgin, I Gurbuzaslan, B Gulec, G Mammadova, G.
Hasanova. Engineering,production and characterization of Spike and Nucleocapsid
structural proteins of SARS–CoV-2 in Nicotiana benthamiana as vaccine candidates
against COVID-19 . bioRxiv.
12. Tarlan Mamedov, Kader Cicek, Kazutoyo Miura , Burcu Gulec, Ersin Akinci and Gunay
Mammadova,Gulnara Hasanova. A Plant-Produced in vivo deglycosylated full-length
Pfs48/45 as a Transmission-Blocking Vaccine Candidate against malaria . Scientific
Reports 9 (1), 2019, DOI: 10.1038/s41598-019-46375-6.
13. Mamedov T, Musayeva I, Acsora R, Gun N, Gulec B, Mammadova G, Cicek K,
Hasanova G.Engineering, and production of functionally active human Furin in N.
benthamiana plant: In vivo post-translational processing of target proteins by Furin in
plants . PLoS One. 2019 Mar12;14(3):e0213438. doi: 10.1371/journal.pone.0213438.
14. Mamedov T, Cicek K, Gulec B, Ungor R, Hasanova G. In vivo production of non-
glycosylated recombinant proteins in Nicotiana benthamiana plants by co-expression
with Endo-β-N-acetylglucosaminidase H (Endo H) of Streptomyces plicatus . PLoS One.
2017 Aug21;12(8):e0183589. doi: 10.1371/journal.pone.0183589.
15. Mamedov T, Chichester JA, Jones RM, Ghosh A, Coffin MV et al. Production of
functionally active and immunogenic non-glycosylated protective antigen from Bacillus
anthracis in Nicotiana benthamiana by co-expression with peptide-N-glycosidase F
(PNGase F) of Flavobacteriummeningosepticum . PLoS One. 2016, 21, 11, 4.
Son güncelleme : 14.11.2023 15:33:13